[Effect of the consumption of krill protein isolates on lysosomal proteinase activity in rats]

A study was made of the total and nonsedimented activity of 4 lysosomal proteinases in the liver, kidneys and blood serum of rats fed for 4 months krill protein isolate (AtlantNIRO) as the only source of protein or that replaced by 50% with a control protein (casein) contained by the 18% protein (in terms of caloricity) diet. The use of the krill isolate as the only source of protein brought about a significant increase in the total activity of cathepsin A and cathepsin D and in nonsedimented activity of cathepsins A, D, B and C in rat liver (by 95, 23, 32 and 50%, respectively). Meanwhile in the kidneys, there was an increase in the total activity of cathepsins A and D. Proteinases A, D, B and C were activated in the blood serum. The 50% replacement of the krill isolate by casein elicited a substantial decrease in the adverse effect of the krill protein isolate on metabolic processes in rats.