Related Experiment Video
Updated: Jun 19, 2025

Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
Exploring the structure of type V deep eutectic solvents by xenon NMR spectroscopy
Matteo Boventi1, Michele Mauri1, Franca Castiglione2
1Department of Materials Science, University of Milano-Bicocca, Via R. Cozzi 55, 20125 Milano, Italy. roberto.simonutti@unimib.it.
Abstract:
Hydrophobic non-ionic (type V) deep eutectic solvents (DESs) have recently emerged as a new class of sustainable materials that have shown unique properties in several applications. In this study, type V DESs thymol : camphor, menthol : thymol and eutectic mixtures (EMs) based on menthol : carboxylic acids with variable chain length, are experimentally investigated using xenon NMR spectroscopy, with the aim to clarify the peculiar nanostructure of these materials. The results, obtained from the analysis of the 129Xe chemical shifts and of the longitudinal relaxation times, reveal a correlation between the deviation from ideality of the DESs and their structure free volume. Furthermore, the effect of varying the composition of DESs and EMs on the liquid structure is also studied.
Related Concept Videos
Chemical Shift: Internal References and Solvent Effects
The internal reference compound generally used in NMR spectroscopy is tetramethylsilane (TMS). TMS is preferred because it is chemically inert, soluble in NMR solvents, and easily removable. Also, the highly shielded methyl protons in TMS yield an intense...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
NMR Spectroscopy of Benzene Derivatives
¹H NMR: Complex Splitting
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied...
Solvents
A...
VSEPR Theory and the Effect of Lone Pairs

