Related Experiment Video
Updated: May 5, 2026
04:48
Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
7.9K
Preoperative Echocardiographically Derived Mean dP/dTic Predicts Early Post-operative Dysfunction in Children
Addison Gearhart1,2, Nikhil Thatte3,4, Sunakshi Bassi5,6
1Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA. addisonsgearhart@gmail.com.
Pediatric Cardiology
|July 24, 2024
Summary
Noninvasive mean dP/dtic measurement predicts postoperative ventricular function in pediatric mitral regurgitation patients. This echocardiographic index shows promise for assessing systolic function after mitral valve intervention.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Cardiac Surgery
Background:
- Mean dP/dtic is a noninvasive echocardiographic measure of ventricular function.
- In adults with mitral regurgitation (MR), mean dP/dtic predicts postoperative ejection fraction (EF).
- Its utility in pediatric congenital heart disease with MR is understudied.
Purpose of the Study:
- To evaluate the utility of echocardiographically derived mean dP/dtic in pediatric patients with MR.
- To compare mean dP/dtic with other indices like Tei index and EF for assessing ventricular function before and after mitral valve surgery.
- To determine if preoperative mean dP/dtic can predict postoperative systolic function.
Main Methods:
- Retrospective study of 61 pediatric patients (0-19 years) with MR undergoing mitral valve repair or replacement (2015-2021).
- Echocardiographic data including mean dP/dtic, Tei index, and EF were collected preoperatively, early postoperatively (median 6 days), and late postoperatively (median 350 days).
- Statistical analysis to compare ventricular function indices and assess correlations between preoperative and postoperative measurements.
Main Results:
- Mitral valve intervention was associated with an initial decline in EF and mean dP/dtic, followed by recovery.
- Preoperative mean dP/dtic correlated significantly with both early and late postoperative EF.
- Preoperative EF correlated with late postoperative EF but not significantly with early postoperative EF.
Conclusions:
- Noninvasive mean dP/dtic may be a more sensitive predictor of postoperative systolic function than EF in pediatric patients with MR.
- Mitral valve intervention impacts systolic function, with initial decline and subsequent recovery.
- Mean dP/dtic offers potential advantages for preoperative assessment of ventricular function in this population.
Related Concept Videos
01:27Mitral Valve Prolapse I: Introduction
1.1K
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
1.1K
01:22Mitral Valve Prolapse II: Assessment and Management
1.4K
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
1.4K
01:23Mitral Regurgitation II: Clinical Features and Diagnostic Tests
947
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
947
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
564
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
564
01:30Cardiomyopathy II: Dilated Cardiomyopathy
798
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
798