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Updated: Jun 19, 2025

Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
Published on: October 15, 2019
Photoswitchable Catalysis by a Self-Assembled Molecular Cage
Ray G DiNardi1, Samina Rasheed1, Simona S Capomolla1
1School of Chemistry, UNSW Sydney, Sydney, New South Wales 2052, Australia.
Abstract:
A heteroleptic [Pd2L2L'2]4+ coordination cage containing a photoswitchable azobenzene-derived ligand catalyzes the Michael addition reaction between methyl vinyl ketone and benzoyl nitromethane within its cavity. The corresponding homoleptic cages are catalytically inactive. The heteroleptic cage can be reversibly disassembled and reassembled using 530 and 405 nm light, respectively, allowing catalysis within the cage to be switched OFF and ON at will.
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