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Related Experiment Video

Updated: Jun 19, 2025

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
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Published on: June 16, 2022

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Urethral Bulking.

Nicole Fleischmann1, Bilal Chughtai2, Andre Plair3

  • 1From the White Plains Hospital/Montefiore System, White Plains, NY.

Urogynecology (Philadelphia, Pa.)
|July 25, 2024
PubMed
Summary

Urethral bulking agents (UBAs) offer a treatment option for stress urinary incontinence (SUI). While effective for some, patients need counseling on risks and limited long-term data for these SUI treatments.

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Area of Science:

  • Urology
  • Female Pelvic Medicine

Background:

  • Stress urinary incontinence (SUI) significantly impacts quality of life.
  • Urethral bulking agents (UBAs) represent a minimally invasive treatment option for SUI.

Purpose of the Study:

  • To provide clinicians with evidence-based guidance on the use of urethral bulking agents (UBAs) for treating stress urinary incontinence (SUI).

Main Methods:

  • A comprehensive literature search was conducted for studies on urethral bulking agents published from 1960 to 2022.
  • Data extraction focused on study type, participant demographics, bulking agent, efficacy, and complications.

Main Results:

  • 1,594 articles were identified, with 395 studies screened after limiting to specific study types.
  • Polyacrylamide hydrogel showed marginally better safety and durability compared to other agents.

Conclusions:

  • Urethral bulking agents are indicated for demonstrable SUI and can be considered for initial management or persistent/recurrent SUI post-sling.
  • Patients require counseling regarding risks, limited long-term efficacy, potential repeat procedures, and future implications.
  • Prioritizing UBAs over surgery may be suitable for specific patient groups.