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Updated: Jun 19, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Synthesis and application of well-defined [Ph4P]+[Cu(CF2CF3)2]- complex as a versatile pentafluoroethylating reagent
Tao Dong1, Qilong Shen2, Gavin Chit Tsui1,3
1Department of Chemistry, The Chinese University of Hong Kong Shatin, New Territories Hong Kong SAR China gctsui@cuhk.edu.hk.
Abstract:
We herein describe the preparation and application of a new bispentafluoroethylated organocuprate [Ph4P]+[Cu(CF2CF3)2]-. This complex has demonstrated a remarkable range of reactivities towards carboxylic acids, diazonium salts, organic halides, boronic esters, terminal alkynes and (hetero)arenes as a versatile pentafluoroethylating reagent. The construction of C(sp3)-/C(sp2)-/C(sp)-CF2CF3 bonds can therefore be achieved using a single reagent.
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