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Probiotics in Functional Gastrointestinal Disorders.

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Probiotics like Limosilactobacillus reuteri and Bifidobacterium lactis show promise for treating infantile colic in breastfed babies. Limited evidence also supports their use for functional abdominal pain and irritable bowel syndrome in children.

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Area of Science:

  • Pediatric Gastroenterology
  • Microbiology
  • Dietary Interventions

Background:

  • Functional gastrointestinal disorders (FGID) are common in children, with limited treatment options.
  • Dietary interventions, particularly probiotics, are increasingly explored for FGID management.
  • This chapter reviews current evidence on probiotic efficacy for pediatric FGIDs.

Purpose of the Study:

  • To summarize evidence and provide recommendations for using probiotics in treating common pediatric FGIDs.
  • To highlight specific probiotic strains with the strongest supporting data.
  • To inform clinical practice regarding probiotic supplementation for childhood FGIDs.

Main Methods:

  • Systematic review of existing literature on probiotic use for pediatric FGIDs.
  • Analysis of clinical trial data and expert recommendations.
  • Focus on specific FGIDs: infantile colic, functional abdominal pain (FAP), and irritable bowel syndrome (IBS).

Main Results:

  • Strongest evidence supports Limosilactobacillus (L.) reuteri DSM 17938 and Bifidobacterium animalis subsp. lactis BB-12 for infantile colic in breastfed infants.
  • Limited but encouraging evidence exists for Lacticaseibacillus rhamnosus GG (LGG) in treating pediatric IBS.
  • L. reuteri DSM 17938 shows potential for managing FAP in children.

Conclusions:

  • Specific probiotic strains demonstrate efficacy in treating certain pediatric FGIDs.
  • L. reuteri DSM 17938 and B. lactis BB-12 are recommended for infantile colic.
  • Further research is warranted for other FGIDs and probiotic strains.