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Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
The Preoperative Factors for the Undercorrection of Myopia in an Extend Depth-of-Focus Intraocular Lens: A
Chia-Yi Lee1,2,3, Hung-Chi Chen4,5,6, Ie-Bin Lian7
1Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
High preoperative myopia and corneal refractive power increase the risk of residual myopia after extend depth-of-focus (EDOF) intraocular lens (IOL) implantation, particularly in high-myopia patients.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Intraocular Lenses
Background:
- Undercorrection after intraocular lens (IOL) implantation can lead to suboptimal visual outcomes.
- Extend depth-of-focus (EDOF) IOLs aim to provide a range of vision, but residual refractive errors can still occur.
Purpose of the Study:
- To identify risk factors associated with undercorrection (residual myopia) following EDOF IOL implantation.
- To analyze preoperative biometric and refractive parameters that predict postoperative residual refractive error.
Main Methods:
- Retrospective case-control study including patients with EDOF IOL implantation.
- Patients categorized into residual and non-residual myopia groups based on postoperative sphere power.
- Generalized linear model used to determine odds ratios for residual myopia.
Main Results:
- Postoperative uncorrected visual acuity was worse in the residual myopia group.
- Higher preoperative cycloplegic sphere power, total corneal refractive power (TCRP), corneal cylinder, and axial length (AXL) were significant risk factors for residual myopia.
- These factors, along with anterior chamber depth (ACD) and white-to-white (WTW) distance, were particularly associated with residual myopia in high-myopia patients.
Conclusions:
- High preoperative myopia and corneal refractive power are key risk factors for residual myopia after EDOF IOL implantation.
- The risk is amplified in patients with high myopia, with additional factors like ACD and WTW playing a role.
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