Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

208
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
208
Anorexia Nervosa01:28

Anorexia Nervosa

56
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
56
Taste Buds and Receptors01:20

Taste Buds and Receptors

1.9K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
1.9K
Bulimia Nervosa01:30

Bulimia Nervosa

61
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
61
Assessment of the Gastrointestinal System II: Health Perception Pattern01:29

Assessment of the Gastrointestinal System II: Health Perception Pattern

87
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
87

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of E-Selectin with Inflammation, Mineral and Bone Disorder, and Endothelial Dysfunction in Hemodialysis Patients.

International journal of molecular sciences·2026
Same author

The Bidirectional Relationship Between Type 1 Diabetes Mellitus and Obesity in Pediatric Patients: A Systematic Review.

Children (Basel, Switzerland)·2026
Same author

Discrepancy Between Biological Activity and Functional Fracture Healing Following Vitamin K2 Supplementation in an Ovariectomized Rat Model of Osteoporosis.

Journal of clinical medicine·2026
Same author

The Microbiota-Endometriosis Axis: An Immune-Endocrine Integration Model and Emerging Therapeutic Targets.

International journal of molecular sciences·2026
Same author

Comparative Analysis of Gut Microbiota Patterns in Irritable Bowel Syndrome, Anxiety, and Autoimmune Disorders.

Biomedicines·2026
Same author

Uncoupling Erythropoiesis from Cardiorenal Effects: SGLT2 Inhibition in Non-Diabetic Heart Failure.

Medicina (Kaunas, Lithuania)·2026

Related Experiment Video

Updated: Jun 18, 2025

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

10.9K

Post-COVID-19 Changes in Appetite-An Exploratory Study.

Georgeta Inceu1,2, Ruben Emanuel Nechifor3, Adriana Rusu1,2

  • 1Department of Diabetes and Nutrition Diseases, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.

Nutrients
|July 27, 2024
PubMed
Summary
This summary is machine-generated.

COVID-19 infection may alter eating behavior by increasing appetite hormones like ghrelin and neuropeptide Y (NPY). These changes correlate with brain activity in appetite regulation areas, persisting post-infection.

Keywords:
COVID-19appetitefMRIghrelinneuropeptide Y

More Related Videos

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
10:29

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans

Published on: June 4, 2014

20.2K
Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
07:33

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System

Published on: May 8, 2020

10.4K

Related Experiment Videos

Last Updated: Jun 18, 2025

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

10.9K
Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
10:29

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans

Published on: June 4, 2014

20.2K
Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
07:33

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System

Published on: May 8, 2020

10.4K

Area of Science:

  • Neuroscience
  • Endocrinology
  • Psychology

Background:

  • COVID-19 has been linked to various long-term health effects.
  • Eating behavior is a complex process influenced by hormonal and neural signals.
  • The impact of COVID-19 on appetite regulation remains incompletely understood.

Purpose of the Study:

  • To investigate the persistent effects of COVID-19 on eating behavior and appetite regulation.
  • To compare hormonal profiles and brain activity related to appetite in individuals with and without a history of COVID-19.

Main Methods:

  • Cross-sectional analysis of 55 adults (<50 years, without overweight/obesity) from two groups: non-COVID-19 (n=27) and COVID-19 history (n=28).
  • Assessed hunger, eating behaviors (TFEQ-18), plasma ghrelin, neuropeptide Y (NPY), and resting-state functional MRI (fMRI).
  • Analyzed brain activity using voxel-based regional homogeneity (ReHo) and degree of centrality (DC) for neuronal synchronicity and connectivity.

Main Results:

  • The COVID-19 group exhibited significantly higher plasma ghrelin (197.5 vs. 67.1 pg/mL) and NPY (128.0 vs. 84.5 pg/mL) levels compared to the non-COVID-19 group (p < 0.001 and p = 0.005, respectively).
  • NPY levels positively correlated with ReHo and DC in the left lingual gyrus, a region involved in appetite regulation.
  • No significant differences were found in cognitive restraint, uncontrolled eating, or emotional eating scores between the groups (p > 0.05).

Conclusions:

  • Persistent elevation of appetite-related hormones (ghrelin, NPY) is observed long after COVID-19 infection.
  • Increased NPY levels are associated with altered neural activity in brain regions governing appetite.
  • COVID-19 may lead to lasting changes in the neuroendocrine regulation of appetite, despite stable eating behavior patterns.