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Updated: Aug 10, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
A molecular imprinted ratiometric fluorescence sensor based on blue/orange MXene quantum dots for visual detection of
Tianyao Wang1, Yu Wang2, You Zeng2
1Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China.
Abstract:
Histamine is a highly toxic biogenic amine in food, making its sensitive and rapid detection methods vital for the assurance of edible safety and human health. Here, we explored for the first time a smartphone-enabled ratiometric imprinted fluorescence sensor based on blue/orange MXene quantum dots (MQDs) for fluorescence and visual detection of histamine. A linear relationship between the concentration of histamine and the fluorescence response of the sensor was found in the range of 1-60 μM with a limit of detection (LOD) of 21.9 nM for fluorescence detection and 92.2 nM for visual detection. In addition, the method was validated for the detection of real samples with excellent recoveries from 96.52% to 105.32%. Therefore, this work greatly expands the application of MQDs in the fluorescence sensing field, as well as provides a visual strategy for in-situ detection of histamine in food.

