Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Function Tests

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Respiratory Volumes and Capacities I

Respiratory Volumes and Capacities I

Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...

Respiratory Volumes and Capacities

Respiratory Volumes and Capacities

The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Respiratory Volumes

Respiratory Volumes

Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Elevated <i>D</i> <sub>LCO</sub> and pulmonary function evolution during treatment in a patient with hyperleukocytosis and leukostasis.

Breathe (Sheffield, England)·2026

Same author

Evaluation of the performance of the reference equations for single-breath diffusing capacity of the lung for carbon monoxide (DLCOsb) in Latin American populations at different altitudes: A multicentre study.

Pulmonology·2026

Same author

Joint statement from GOLD/GLI regarding the use of spirometry to define airflow obstruction and diagnose COPD.

The European respiratory journal·2026

Same author

Improved Pulmonary Gas Exchange at Altitude Is Due to Pulmonary Vascular Adaptation to Chronic Hypoxia in Urban Residents.

High altitude medicine & biology·2025

Same author

Technical aspects and interpretation of oscillometry.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2025

Same author

Functional respiratory evaluation in the coronavirus disease-19 era: The role of pulmonary function test laboratories.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion·2025

Same journal

Thoracic Sympathectomy for Harlequin Syndrome.

Archivos de bronconeumologia·2026

Same journal

Prognostic Significance of Electrocardiographic Findings in Hemodynamically Stable Patients With Acute Pulmonary Embolism: Insights From the RIETE Registry.

Archivos de bronconeumologia·2026

Same journal

Endothelial and Angiogenic Biomarkers in Obstructive Sleep Apnea: Longitudinal Associations With Continuous Positive Airway Pressure.

Archivos de bronconeumologia·2026

Same journal

Robotic Resection of Ectopic Paratracheal Thymoma: A Case Report.

Archivos de bronconeumologia·2026

Same journal

Real-World Effectiveness of Tezepelumab Across T2 and Non-T2 Severe Asthma Phenotypes: A Multicenter Spanish Cohort Study.

Archivos de bronconeumologia·2026

Same journal

Mitochondrial Dysfunction and Telomeric Shortening as Long-term Complications After COVID-19.

Archivos de bronconeumologia·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 18, 2025

Conducting Respiratory Oscillometry in an Outpatient Setting

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

Changes in the Functional Classification of Spirometry Using the New Interpretation Standard 2022: A Multicenter

Santiago C Arce¹, Carlos Aguirre-Franco², Patricia Schonffeldt-Guerrero³

¹Instituto de Investigaciones Médicas A. Lanari, Universidad de Buenos Aires, Argentina.

Archivos De Bronconeumologia

|July 27, 2024

Summary

This summary is machine-generated.

The 2022 pulmonary function test standards significantly alter diagnoses, reclassifying many obstructive cases and bronchodilator responses. These updates impact lung disease diagnosis and treatment strategies, especially in different age groups.

Keywords:

Bronchodilation Interpretation Pulmonary function tests Spirometry

More Related Videos

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

Related Experiment Videos

Last Updated: Jun 18, 2025

Conducting Respiratory Oscillometry in an Outpatient Setting

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

Area of Science:

Pulmonary Medicine
Respiratory Diagnostics
Clinical Research

Background:

Pulmonary function tests (PFTs) are crucial for diagnosing and monitoring lung diseases.
The European Respiratory and American Thoracic Societies (ERS/ATS) released updated PFT interpretive standards in 2022, differing from the 2005 guidelines.
Key changes include lung volume integration, z-scores, revised severity categories, and updated bronchodilator response criteria.

Purpose of the Study:

To compare spirometry results using the 2005 and 2022 ATS/ERS interpretive standards.
To assess the impact of the 2022 standards on diagnostic classifications and bronchodilator response assessments.
To analyze variations in severity categorization across different age groups under the new standards.

Main Methods:

Retrospective, multi-center study utilizing spirometric data from 2002-2022.
Categorization of spirometry results according to both 2005 and 2022 ATS/ERS standards.
Calculation of predicted values using the GLI 2012 equation for the Caucasian subset.

Main Results:

A significant shift was observed, with 23% of subjects reclassified from obstructive to mixed pattern diagnoses under the 2022 standards, indicating a need for lung volume assessments.
12.3% of bronchodilator responders were reclassified as non-responders using the 2022 criteria.
Severity classifications varied by age, with older patients receiving milder classifications and younger patients receiving more severe ones under the 2022 standards.

Conclusions:

The 2022 standards may increase the utilization of lung volume assessments and more complex pulmonary function tests.
Bronchodilator responsiveness was more prevalent in extreme age groups and those with milder spirometric impairments.
These changes could influence clinical decision-making, potentially leading to earlier treatment initiation or de-escalation based on revised severity assessments.