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Updated: Jun 18, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Skin cancer classification based on an optimized convolutional neural network and multicriteria decision-making
Neven Saleh1,2, Mohammed A Hassan3, Ahmed M Salaheldin4
1Systems and Biomedical Engineering Department, Higher Institute of Engineering, EL Shorouk Academy, Cairo, Egypt. nesaleh@msa.edu.eg.
This study developed 51 artificial intelligence models for skin cancer classification, finding the AlexNet convolutional neural network with grey wolf optimization achieved 94.5% accuracy. Feature reduction improved classification and reduced training time.
Area of Science:
- Dermatology and Artificial Intelligence
- Computational Pathology
- Medical Image Analysis
Background:
- Early detection of skin cancer is crucial for effective treatment.
- Numerous artificial intelligence models exist for skin cancer detection, but optimal model selection is often overlooked.
- Benchmarking various models is essential for advancing AI in skin cancer diagnostics.
Purpose of the Study:
- To develop and compare multiple artificial intelligence models for skin cancer classification.
- To identify the optimal model for skin cancer classification through a systematic benchmarking process.
- To evaluate the impact of feature reduction techniques on model performance.
Main Methods:
- Utilized four convolutional neural network (CNN) architectures (AlexNet, Inception V3, MobileNet V2, ResNet 50) for feature extraction.
- Implemented feature reduction using the grey wolf optimizer (GWO) algorithm and compared with original features.
- Classified skin cancer images into four classes using six machine learning (ML) classifiers, resulting in 51 distinct models.
- Employed the RAPS (ranking alternatives by perimeter similarity) multicriteria decision-making approach for model selection.
- Trained and tested models on the International Skin Imaging Collaboration (ISIC) 2017 dataset.
Main Results:
- The AlexNet CNN combined with the classical GWO algorithm for feature reduction emerged as the optimal model.
- This optimal model achieved a high classification accuracy of 94.5% on the ISIC 2017 dataset.
- Feature reduction using GWO demonstrated benefits in reducing training time and enhancing classification accuracy.
- The RAPS method proved effective in robustly selecting the best-performing model among the 51 developed.
Conclusions:
- This study provides a comprehensive benchmark for skin cancer classification models.
- The optimal model, AlexNet with GWO, offers a promising approach for accurate and efficient skin cancer detection.
- Feature reduction techniques are vital for improving AI model performance in medical image analysis.
- The RAPS method is a valuable tool for selecting optimal AI models in complex classification tasks.
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