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Related Concept Videos

Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
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Cystic Fibrosis: Management01:24

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Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
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Liver Histology01:27

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
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Liver Physiology01:30

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
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The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
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Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

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The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
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Related Experiment Video

Updated: Jan 27, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
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Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

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[Cystic liver].

C Reuteler, J Teuscher

    Schweizerische Medizinische Wochenschrift
    |October 19, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Polycystic liver disease often accompanies polycystic kidney disease, causing abdominal pain from mechanical effects rather than liver failure. Early diagnosis and management are key for patients with this hereditary condition.

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    Area of Science:

    • Hepatology and Nephrology
    • Genetics and Hereditary Diseases

    Background:

    • Polycystic kidney disease (PKD) is an inherited disorder.
    • It can occur alongside polycystic liver disease (PLD).

    Observation:

    • Patients with PKD experiencing abdominal pain may be diagnosed with concurrent PLD.
    • Symptoms in PLD are typically mechanical, not indicative of liver function impairment.

    Findings:

    • Both PKD and PLD are autosomal dominant hereditary diseases with variable penetrance.
    • Liver function is rarely compromised in advanced stages of PLD.

    Implications:

    • Understanding the link between PKD and PLD is crucial for accurate diagnosis.
    • Management focuses on mechanical symptoms, as liver failure is uncommon.