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Increase in measles cases in a City hospital, Istanbul, Turkey

Mehmet Karabey1, Nuran Karabulut1, Sema Alaçam1

  • 1Department of Medical Virology, Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey.

Central European Journal of Public Health
|July 28, 2024
PubMed
Abstract

Insights

Measles outbreaks are rising globally. This study found low measles immunity in our region, with most cases unvaccinated and under 18, highlighting vaccination program gaps.

Area of Science:

  • Virology
  • Epidemiology
  • Immunology

Background:

  • Measles incidence is increasing globally and nationally.
  • Understanding regional measles epidemiology and seroprevalence is crucial for public health strategies.

Purpose of the Study:

  • To investigate the epidemiological and clinical characteristics of measles cases.
  • To determine measles seroprevalence in the region.
  • To assess the impact of vaccination on measles cases.

Main Methods:

  • Retrospective study of 7,452 individuals from December 2021 to March 2023.
  • Analysis of measles IgG and IgM antibodies using enzyme-linked immunosorbent assay.
  • Data collected from electronic medical records, including demographics, symptoms, and vaccination status.

Main Results:

  • 102 measles cases identified; 75.5% were under 18 years old.
  • 90% of cases with known vaccination status were unvaccinated.
  • Overall measles seroprevalence was 72.8%, with lower rates in infants (4.8% in 8-11 months) but the highest case incidence in this group.

Conclusions:

  • Measles immunity is insufficient in the region, posing a significant public health risk, especially for individuals under 18.
  • The rise in measles cases underscores the need for stricter and more decisive implementation of vaccination programs.
Keywords:
Istanbulmeaslesmeasles outbreakseroprevalencevaccination

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