Related Experiment Video
Updated: Jun 18, 2025
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
20.3K
Palliative Radiotherapy for Symptomatic Primary Tumors in Patients With Locally Advanced Breast Cancer
Jae Sik Kim1, Jee Suk Chang2, Kyubo Kim3,4
1Department of Radiation Oncology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
Journal of Breast Cancer
|July 29, 2024
Summary
Palliative radiotherapy (RT) helps manage advanced breast cancer symptoms. Further research is needed for optimized RT regimens to improve durable local control and patient outcomes.
Area of Science:
- Oncology
- Radiotherapy
- Breast Cancer Management
Background:
- Advanced breast cancer significantly impacts quality of life.
- Palliative radiotherapy (RT) is crucial for symptom management.
- Increased survival necessitates effective retreatment and durable local control.
Purpose of the Study:
- To review current evidence on palliative RT for symptomatic breast cancer.
- To summarize efficacy, outcomes, and toxicity profiles.
- To identify needs for optimized RT regimens and future research.
Main Methods:
- Comprehensive literature review of palliative radiotherapy for breast cancer.
- Analysis of evidence on efficacy, outcomes, and toxicity.
- Synthesis of data on dose fractionation, radiobiology, and RT techniques.
Main Results:
- Palliative RT is effective in managing symptomatic breast cancer.
- Diverse RT approaches exist due to varying disease severity and objectives.
- Optimal dose fractionation and advanced techniques require further exploration.
Conclusions:
- Current palliative RT strategies offer symptom relief but require optimization.
- Evolving treatment landscapes necessitate tailored RT regimens.
- Further research is essential to address patient and physician expectations and improve outcomes.
