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Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
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[Anaesthesiological Management of Traumatic Brain Injury]

Raphael-Donatus Hein, Jan Arne Blancke, Stefan J Schaller

    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
    |July 29, 2024
    PubMed

    Abstract:

    Traumatic brain injury (TBI) is the main cause of death in people < 45 years in industrial countries. Minimising secondary injury to the injured brain is the primary goal throughout the entire treatment. Anaesthesiologic procedures aim at the reconstitution of cerebral perfusion and homeostasis. Both TBI itself as well as accompanying injuries show effects on cardiac and pulmonary function. Time management plays a crucial role in ensuring a safe anaesthesiologic environment while minimizing unnecessary procedures. Furthermore, growing medical drug pre-treatment demands for further knowledge e.g., in antagonization of anticoagulation.

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