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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jun 18, 2025

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

High b-Value and Ultra-High b-Value Diffusion Weighted MRI in Stroke.

Rifeng Jiang¹, ZhenXiong Wang², Jun Liu³

¹Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.

Journal of Magnetic Resonance Imaging : JMRI

|July 29, 2024

Summary

High and ultra-high b-value diffusion-weighted imaging (DWI) show promise for evaluating stroke lesions. These advanced DWI techniques provide more comprehensive data than standard DWI for noninvasive stroke assessment.

Keywords:

diffusion weighted MR imaging ischemic infarction

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Published on: November 8, 2012

Area of Science:

Radiology
Neuroimaging
Medical Diagnostics

Background:

Diffusion-weighted imaging (DWI) is crucial for detecting acute ischemic stroke.
Standard b-value DWI (SB-DWI) has limitations in fully characterizing lesion extent.
Exploring advanced DWI techniques can improve noninvasive stroke evaluation.

Purpose of the Study:

To assess the clinical utility of high b-value DWI (HB-DWI) and ultra-high b-value DWI (UB-DWI) for noninvasive evaluation of ischemic infarctions.
To compare the lesion volume and diffusion parameter correlations of HB-DWI and UB-DWI against SB-DWI.

Main Methods:

Prospective study involving 64 patients with clinically diagnosed ischemic lesions.
Utilized 3.0 T MRI with multi-b-value DWI (SB-DWI, HB-DWI, UB-DWI) and q-space sampling sequences.
Analyzed lesion segmentation, fractional anisotropy (FA), and apparent diffusion coefficients (ADCs) at various b-values.

Main Results:

HB-DWI and UB-DWI detected various signal intensities in stroke lesions not seen on SB-DWI.
Abnormality volumes were significantly larger with HB-DWI and UB-DWI compared to SB-DWI.
Significant correlations were found between FA and ADCs at higher b-values (4000 and 10,000 s/mm²).

Conclusions:

HB-DWI and UB-DWI demonstrate potential as valuable supplementary tools for noninvasive stroke lesion evaluation.
These advanced DWI techniques offer enhanced sensitivity and characterization of ischemic infarctions.
Further integration into clinical practice may improve diagnostic accuracy for stroke.