Related Experiment Video
Updated: Jun 18, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
Management of Chronic Heart Failure in Dialysis Patients: A Challenging but Rewarding Path
Luxuan Guo1,2,3, Yue Ji4, Tianhao Sun1,2,3
1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 300193 Tianjin, China.
Insights
Heart failure (HF) management in dialysis patients requires tailored approaches due to unique health challenges. This review offers new perspectives on diagnosing and treating HF in this population.
Area of Science:
- Nephrology
- Cardiology
- Internal Medicine
Background:
- Chronic heart failure (CHF) is a leading cause of mortality in dialysis patients.
- Existing heart failure (HF) guidelines are often inadequate for dialysis populations due to renal dysfunction and treatment specifics.
- There is a critical need for evidence-based strategies for managing HF in patients undergoing dialysis.
Purpose of the Study:
- To review and synthesize current knowledge on HF management in dialysis patients.
- To highlight the differences in HF diagnosis and treatment between the general population and dialysis patients.
- To provide updated perspectives and future directions for clinical practice.
Main Methods:
- Comprehensive literature review of existing guidelines and clinical studies.
- Focus on staging, diagnosis, risk factor management, pharmacotherapy, and dialysis-specific treatments for HF.
- Analysis of evidence-based medicine and clinical trial data.
Main Results:
- Dialysis patients present unique challenges in HF management compared to the general population.
- Current guidelines require adaptation to address the specificities of hemodialysis (HD) and peritoneal dialysis (PD).
- The review synthesizes new insights into HF diagnosis and treatment for this cohort.
Conclusions:
- Standard HF guidelines need modification for dialysis patients.
- A tailored, evidence-based approach is crucial for optimizing HF care in dialysis populations.
- This review aims to standardize and improve clinical understanding and management of HF in patients on dialysis.
Abstract:
Chronic heart failure (CHF) is a common complication and cause of death in dialysis patients. Although several clinical guidelines and expert consensus on heart failure (HF) in the general population have been issued in China and abroad, due to abnormal renal function or even no residual renal function (RRF) in dialysis patients, the high number of chronic complications, as well as the specificity, variability, and limitations of hemodialysis (HD) and peritoneal dialysis (PD) treatments, there are significant differences between dialysis patients and the general population in terms of the treatment and management of HF. The current studies are not relevant to all dialysis-combined HF populations, and there is an urgent need for high-quality studies on managing HF in dialysis patients to guide and standardize treatment. After reviewing the existing guidelines and literature, we focused on the staging and diagnosis of HF, management of risk factors, pharmacotherapy, and dialysis treatment in patients on dialysis. Based on evidence-based medicine and clinical trial data, this report reflects new perspectives and future trends in the diagnosis and treatment of HF in dialysis patients, which will further enhance the clinicians' understanding of HF in dialysis patients.
Related Concept Videos
Heart Failure Drugs: Diuretics
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Pathophysiology of Heart Failure
Heart Failure Drugs: β-Blockers
Heart Failure Drugs: Inotropic Agents

