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Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP
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SARS-CoV-2 Polymerase Chain Reaction Cycle Threshold Trends in Patients Who Are Immunocompromised and Implications
Courtney E Harris1, Vineeta Vaidya2, Zhou Lan3
1Division of Infectious Disease, Medical University of South Carolina, Charleston, South Carolina, USA.
Open Forum Infectious Diseases
|July 30, 2024
Abstract:
Among 495 patients who were immunocompromised and tested positive for SARS-CoV-2, polymerase chain reaction cycle thresholds remained <33 beyond 20 days more frequently in patients with hematologic malignancies, particularly those receiving B-cell-depleting or Bruton tyrosine kinase inhibitor therapy, as compared with those with solid organ malignancy (26% vs 5%).
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