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Impact of COVID-19 on Emergency Management of Acute Type A Aortic Dissection: A Single-Center Historic Control Study
Rui Zhao1, Wei Xu2, Zhao Wang3
1Department of Cardiovascular Surgery, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037 Beijing, China.
Insights
The COVID-19 pandemic reduced emergency acute type A aortic dissection (ATAAD) cases and surgeries, but in-hospital mortality remained stable. Surgical timing and emergency department stays varied during the pandemic.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- The COVID-19 pandemic significantly impacted healthcare systems globally.
- Understanding its effect on emergency management of critical conditions like acute type A aortic dissection (ATAAD) is crucial.
Purpose of the Study:
- To assess the impact of the 2020 COVID-19 pandemic on the emergency management of acute type A aortic dissection (ATAAD).
- To compare patient demographics, treatment strategies, and outcomes during the pandemic versus a historical control period.
Main Methods:
- A retrospective study comparing 337 ATAAD patients from January to June 2020 (pandemic) with 189 patients from the same period in 2019 (control).
- Primary outcome: in-hospital death. Secondary outcomes included automatic discharge and changes in treatment patterns.
- Analysis of factors influencing outcomes across different epidemic stages.
Main Results:
- No significant difference in in-hospital mortality between 2020 (20.5%) and 2019 (17.4%).
- A significant decrease in the proportion of patients receiving surgical treatment in 2020 (50.0%) compared to 2019 (68.25%).
- Shorter surgery times for ATAAD patients in 2020 (6.46 hours) versus 2019 (7.33 hours); length of stay in the emergency department varied by epidemic stage.
Conclusions:
- The COVID-19 outbreak led to fewer ATAAD patients and reduced surgical interventions, without increasing overall mortality.
- Surgical strategies adapted, with initial trends toward longer pre-operative intervals, normalizing later in the epidemic.
- Effective epidemic prevention measures are vital to protect non-infected patients and maintain essential medical services.
Background:
The present study aimed to clarify the impact of the 2020 COVID-19 pandemic on emergency management of acute type A aortic dissection.
Methods:
We consecutively enrolled 337 acute type A aortic dissection (ATAAD) patients at emergency room in Fuwai Hospital (Beijing, China) from January to June during the 2020 COVID-19 epidemic (n = 148) and the same period in 2019 as the historical control (n = 189). The primary outcome was defined as in-hospital death. Other outcomes included automatic discharge during emergency admission. The factors with significant differences before and after the epidemic were compared and analyzed by stages with the study endpoint to clarify their changes in different stages of the epidemic.
Results:
There was no significant difference in in-hospital mortality (35 (20.5%) vs. 23 (17.4%), p = 0.472). Compared with year 2019, proportion of patients receiving surgical treatment decreased significantly (74 (50.0%) vs. 129 (68.25%), p 0.001). The surgery time of ATAAD patients in 2020 was significantly shorter (6.46 [5.52, 7.51] vs. 7.33 [6.00, 8.85] hours, p = 0.01). The length of stay in the emergency department significantly differed at each stage.
Conclusions:
Our study demonstrated a significant reduction in the number of ATAAD patients and surgical treatment during COVID-19 outbreak. The surgical strategy of patients changed, but the overall mortality was largely the same. Patients undergoing surgery had a trend toward longer interval from the onset to the operating room, but they tended to be normal at the end of the epidemic. Proper epidemic prevention policies may avoid COVID-19 hitting patients who are not infected with the virus to the greatest extent.
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