Related Experiment Video

Updated: May 11, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.4K

Paediatric postoperative acute kidney injury after non-cardiac surgery: Protocol for a systematic review and

Arash Emami1, Ebba Sivertsson1, Johan Westerbergh2

  • 1Anesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Acta Anaesthesiologica Scandinavica
|July 30, 2024
PubMed

Insights

This systematic review examines pediatric acute kidney injury (AKI) after non-cardiac surgery. Understanding its incidence is crucial for improving outcomes in young patients undergoing these procedures.

Area of Science:

  • Pediatric Nephrology
  • Surgical Outcomes Research
  • Critical Care Medicine

Background:

  • Pediatric acute kidney injury (AKI) is linked to severe complications, including mortality and chronic kidney disease.
  • Postoperative AKI is well-documented in adults and pediatric cardiac surgery patients.
  • The incidence of AKI following pediatric non-cardiac surgery remains unclear.

Purpose of the Study:

  • To systematically review and assess the incidence of AKI in pediatric patients after non-cardiac surgery.
  • To synthesize current evidence on pediatric postoperative AKI in non-cardiac settings.
  • To establish a foundation for future research in this understudied area.

Main Methods:

  • Systematic review of observational studies and randomized controlled trials.
  • Literature search across PubMed, Cochrane, and Web of Science databases.
  • Data extraction and risk of bias assessment by independent reviewers, adhering to PRISMA and GRADE guidelines.

Main Results:

  • The review will quantify the incidence of pediatric postoperative AKI after non-cardiac surgery.
  • Analysis of risk of bias will assess the quality of included studies.
  • Potential for meta-analysis if study homogeneity permits.

Conclusions:

  • This review will elucidate the incidence of AKI in pediatric non-cardiac surgery.
  • Findings will inform clinical practice and guide future research priorities.
  • Improved understanding of pediatric postoperative AKI is expected to enhance patient care and outcomes.
Abstract

Keywords:
acute kidney injuryanaesthesiachildcreatininefluid balancepostoperative complicationsrenal failurerenal replacement therapy

More Related Videos

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.2K
Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock07:48

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock

Published on: October 28, 2022

1.2K

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...