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Aquablation at 4-years: Real World Data From the Largest Single-center Study With Associated Outcomes Follow-up
Olamide O Omidele1, Alexandra S Siegal1, Reza Roshandel1
1Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY.
Urology
|July 31, 2024
Summary
Aquablation therapy for benign prostatic hyperplasia (BPH) shows durable safety and efficacy over 4 years. This robotic procedure significantly improves urinary symptoms and flow rate while preserving ejaculation in most men.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Robotic Surgery
Background:
- Benign prostatic hyperplasia (BPH) is a common condition in aging men.
- Symptomatic BPH significantly impacts quality of life.
- Current treatments for BPH have varying efficacy and complication profiles.
Purpose of the Study:
- To evaluate the 4-year safety and efficacy of the Aquablation procedure in men with symptomatic BPH.
- To assess long-term outcomes of robotic-assisted Aquablation therapy.
- To report real-world data on Aquablation for BPH treatment.
Main Methods:
- Prospective, single-center, observational study.
- 330 men with moderate-to-severe BPH treated with robotic-assisted Aquablation.
- Data collected on International Prostate Symptom Score (IPSS), peak urinary flow rate (Qmax), post-void residual (PVR), antegrade ejaculation, and complications over 4 years.
Main Results:
- Significant improvement in IPSS (23.8 to 6.9) and Qmax (6.4 to 17.4 mL/sec) at 4 years.
- Mean prostate volume reduction of 41.3% at 1 year.
- Antegrade ejaculation preserved in 99.6% of men.
- Low complication rates: 11.2% UTI, 3.3% bleeding requiring transfusion, 3.9% re-treatment.
Conclusions:
- Aquablation therapy is a safe and effective treatment for BPH.
- The procedure provides durable symptom relief and functional improvement for up to 4 years.
- Aquablation offers a favorable safety profile with high preservation of antegrade ejaculation.
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