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Individualized dose calculation for internal exposure on radionuclide intake: GPU acceleration approach.

Shuchang Yan1,2, Rui Qiu1,2, Zhen Wu1,2,3

  • 1Department of Engineering Physics, Tsinghua University, Beijing , People's Republic of China.

Physics in Medicine and Biology
|July 31, 2024
PubMed
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This study introduces a fast GPU Monte Carlo simulation for internal radiation dose assessment, enabling personalized calculations from radionuclide intake with high accuracy and significantly reduced computation time.

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Chinese human phantomGPU Monte Carloindividualized dose assessmentinternal exposure

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Area of Science:

  • Medical Physics
  • Computational Dosimetry
  • Radiation Protection

Background:

  • Accurate internal exposure dose assessment is vital for personnel safety.
  • Current methods may lack efficiency and personalization for occupational exposure scenarios.

Purpose of the Study:

  • To develop and validate a precise and efficient GPU Monte Carlo simulation for internal exposure dose calculation.
  • To enable personalized dose assessments from common radioactive nuclide intake.

Main Methods:

  • Developed a GPU-accelerated Monte Carlo program for radionuclide intake simulations.
  • Implemented photoelectronic coupled transport, nuclide simulation, and optimized acceleration.
  • Established personalized phantom construction and simulated various irradiation scenarios.

Main Results:

  • Calculated organ doses with <3% deviation compared to ICRP Publication 133.
  • Achieved 150-500x faster simulation times using GPU vs. CPU.
  • Demonstrated up to 75% difference in organ dose due to posture variations.

Conclusions:

  • Presents a rapid GPU-based simulation for internal irradiation doses.
  • Accommodates individualized phantoms for realistic and expeditious calculations.
  • Provides a feasible tool for precise internal dose calculation in real-world scenarios.