Related Experiment Video
Updated: Jun 18, 2025

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
Published on: August 2, 2024
[Health-Related Quality of Life in Heart Transplant Recipients: A Review]
Eduardo Fasce1, Fabrizio Fasce2, Álvaro Quiñones3
1Departamento de Educación Médica, Facultad de Medicina, Universidad de Concepción, Concepción, Chile.
Background:
Organ transplantation is a therapeutic alternative for patients with end-stage organ failure resulting from chronic or acute disease. In this context, health-related quality of life is an important multidimensional concept to evaluate the benefits of transplantation.
Objective:
To identify changes in health-related quality of life experienced by heart transplant patients.
Methods:
Systematic review of cross-sectional, prospective, qualitative studies published in English from January 2020 to December 2022 in Cochrane Library, Medline, OVID, PubMed, and Web of Science, following PRISMA guidelines.
Results:
We identified forty-three articles, 21 cross-sectional, 10 prospective, and 12 qualitative, in addition to including information on the pre-transplant stage. A significant favorable change in most quality-of-life parameters is verified, which is persistent even after 20 years.
Conclusions:
Heart transplantation represents a successful therapeutic alternative that not only prolongs life but also makes it possible to achieve an adequate health-related quality of life. Family and social support are crucial elements that impact adjustment and quality of life during the pre- and post-transplant process.

