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Updated: Jun 18, 2025

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Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
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Extraperitoneal robot-assisted radical prostatectomy by the da Vinci and Versius System: first comparative analysis.
Francesco Dibitetto1, Roberto Castellucci2, Pierluigi Russo3
1Uroclinic, Clinica Nuova Villa Claudia, Rome, Italy - francescodibitetto@gmail.com.
Minerva Urology and Nephrology
|August 2, 2024
Summary
This study compares the da Vinci and Versius robotic systems for extraperitoneal robot-assisted radical prostatectomy (eRARP). While most outcomes are similar, the Versius system showed a higher rate of positive lymph nodes, warranting further investigation.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Robotic Surgery
Background:
- Robotic-assisted surgery has transformed urology.
- The Versius Surgical System offers a new alternative to the established da Vinci system.
- This study compares outcomes of extraperitoneal robot-assisted radical prostatectomy (eRARP) between these two platforms.
Purpose of the Study:
- To compare the clinical outcomes of eRARP using the da Vinci and Versius robotic systems.
- To present the largest case series to date comparing these two robotic platforms for eRARP.
Main Methods:
- Retrospective analysis of 106 consecutive patients undergoing eRARP.
- Comparison between da Vinci and Versius systems from July 2021 to July 2023.
- Analysis of baseline characteristics, perioperative outcomes, and pathology results by a single surgeon.
Main Results:
- Comparable baseline characteristics, operative time, blood loss, and hospital stay between the two systems.
- Variations observed in pelvic lymphadenectomy rates and nerve-sparing procedures.
- No significant differences in ISUP grades or positive surgical margins, but a higher percentage of positive lymph nodes (Pathological N stage) with Versius.
Conclusions:
- This study represents the largest comparative case series of da Vinci vs. Versius for eRARP.
- Overall surgical outcomes are similar, but differences in lymphadenectomy and Pathological N stage require attention.
- Further research and long-term follow-up are needed to guide optimal robotic system selection in urological surgery.

