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Updated: Jun 18, 2025

05:52
Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
21.9K
Should patients with minor strokes be given thrombolytics?
Xun Wang1, Yi Dong2, Qiang Dong1
1Department of Neurology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Stroke and Vascular Neurology
|August 3, 2024
Summary
Thrombolysis is not superior to antiplatelet therapy for minor non-disabling strokes. Reviewing published studies on thrombolysis for minor stroke patients is crucial for clinical practice.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Clinical Trials
Background:
- Tissue-type plasminogen activator (thrombolysis) is underutilized in mild stroke cases (29-43%).
- Previous research indicated poor outcomes for some patients with mild strokes not receiving thrombolysis.
- Global stroke guidelines now advocate for thrombolysis in minor yet disabling strokes.
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