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804
Association Between the Oxidative Balance Score and Endometriosis: A Population-Based Study
Xiaoming Zhou1, Weiwei Shen1, Jue Zhu2
1Department of Gynecology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, 315010, People's Republic of China.
International Journal of Women'S Health
|August 5, 2024
Summary
A high oxidative balance score (OBS) may reduce endometriosis risk. This suggests dietary and lifestyle factors could play a role in preventing this condition.
Area of Science:
- Reproductive health
- Nutritional science
- Epidemiology
Background:
- Endometriosis is a condition affecting women of reproductive age.
- Oxidative stress is implicated in the pathogenesis of endometriosis.
- Dietary and lifestyle factors influence oxidative balance.
Purpose of the Study:
- To investigate the association between the oxidative balance score (OBS) and endometriosis.
- To explore if OBS can be a potential biomarker for endometriosis risk.
Main Methods:
- Cross-sectional study using NHANES data (1999-2006).
- Calculated OBS based on 16 dietary nutrients and 4 lifestyle factors.
- Used weighted multivariate logistic analysis to assess the association between OBS categories and endometriosis.
Main Results:
- A total of 5095 women were analyzed.
- Higher OBS was associated with lower odds of endometriosis (OR=0.70, P=0.033).
- This association was significant in subgroups with irregular menstruation and female hormone use.
Conclusions:
- A higher oxidative balance score is linked to reduced endometriosis risk.
- Dietary and lifestyle modifications contributing to a higher OBS may be protective against endometriosis.
- The protective effect is more pronounced in specific subgroups.
