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Updated: Jun 18, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Cine clips increase the detection of thyroid pyramidal lobe in routine thyroid sonogram
Yi Yan1,2, Xiaoou He1, Kai Hu3,4
1Department of Radiology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Identifying the thyroid pyramidal lobe is crucial for thyroid cancer surgery. A new ultrasound protocol using cine-loops significantly improves detection rates, aiding in complete thyroid gland removal and preventing recurrence.
Area of Science:
- Endocrinology
- Surgical Oncology
- Radiology
Background:
- The thyroid pyramidal lobe is an anatomical variation that requires identification and resection during thyroid cancer surgery.
- Failure to resect the pyramidal lobe can lead to interval cancer in residual thyroid tissue.
Purpose of the Study:
- To determine the prevalence of the thyroid pyramidal lobe in patients with and without prior thyroidectomy.
- To optimize the ultrasonography protocol for identifying the thyroid pyramidal lobe during routine examinations.
Main Methods:
- A prospective study enrolled 1579 patients undergoing routine thyroid ultrasonography.
- A dedicated scanning protocol was established, including static images and a transverse cine loop from the isthmus to the hyoid bone.
- The presence and features of thyroid pyramidal lobes were evaluated and compared.
Main Results:
- The detection rate of thyroid pyramidal lobes in patients without thyroidectomy increased from 39.5% to 49.7% with the addition of cine-loop imaging.
- Cine-loops were particularly effective in detecting pyramidal lobes separated from the main lobe or in post-thyroidectomy patients.
- The enhanced protocol also identified pathologies on the thyroid pyramidal lobe, including benign and malignant nodules and Hashimoto's thyroiditis pseudo-nodules.
Conclusions:
- Dynamic assessment with cine-loop significantly increases the detection rate of the thyroid pyramidal lobe.
- Attention to the thyroid pyramidal lobe in pre-operative sonographic imaging can prevent incomplete thyroid gland removal during thyroidectomy.
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