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Updated: Jun 18, 2025

In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D
Published on: December 9, 2022
Ophiopogonin D: review of pharmacological activity
Ke-Qian Chen1, Shu-Zhi Wang2, Hai-Bo Lei1
1Department of Clinical Pharmacy, Xiangtan Central Hospital, Xiangtan, China.
Background:
Ophiopogon D is an important natural organic compound in Ophiopogon japonicus, which often has significant biological activity.
Purpose:
The purpose of this review is to systemically summarize and discuss the pharmacological activity and underlying mechanisms of OP-D in recent years.
Method:
PubMed and Web of Science were searched with the keywords:"Ophiopogon japonicus", "Ophiopogon D" "pharmacology", and "pharmacokinetics". There was no restriction on the publication year, and the last search was conducted on 1 Jan 2024.
Results:
Emerging evidence suggests that OP-D possess numerous pharmacological activities, including bone protection, cardiovascular protection, immune regulation, anti-cancer, anti-atherosclerosis, anti-inflammatory and anti-NAFLD.
Conclusion:
OP-D has a potential value in the prevention and treatment of many diseases. We hope that this review will contribute to therapeutic development and future studies of OP-D.
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