The effects of different suture techniques on collagen metabolism in experimental distal colonic anastomoses

Two types of suture techniques have been compared in anastomoses of the distal colon in 20 mongrel dogs. They were divided into four groups, each consisting of five dogs. In A and C groups a single layer suture technique, and in B and D groups a two layer suture technique was used. In order to determine tissue hydroxyproline activities at the suture lines, the anastomosed segments were resected on the fifth day in A and B, and on the tenth day in C and D groups. It was observed that the hydroxyproline activities in single layer anastomoses were higher than those of two layer anastomoses with the implication that there was more rapid wound healing.