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Updated: Jun 17, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Spermatocytic tumor with extensive lymphovascular invasion in a young male
Payal Arvind Chawhan1, Charanjeet Ahluwalia1, Sana Ahuja1
1Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Abstract:
Spermatocytic tumors are rare testicular cancers, accounting for less than 1 % of all testicular neoplasms, usually affecting older men. This report details a 35-year-old male with a spermatocytic tumor featuring extensive lymphovascular invasion. The patient had a painless, slow-growing right testicular mass, with normal serum tumor markers. Ultrasound and CT scans suggested malignancy. Post-orchiectomy, histopathology confirmed a spermatocytic tumor with polymorphic cells and lymphovascular invasion. Immunohistochemical staining was positive for SALL4 and CD117, negative for OCT4, AFP, and CD30. The patient underwent chemotherapy and remained recurrence-free for a year, highlighting the need for accurate diagnosis and long-term monitoring.

