Related Experiment Video
Updated: Jun 17, 2025

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
Published on: January 10, 2019
Potential S1 Nerve Root Blocks Associated with Sacroiliac Joint Injections
Andrew Ng1, Jesse Lou1, Dajie Wang1
1Department of Anesthesiology Jefferson Pain Center Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Sacroiliac joint injections can cause temporary leg numbness by affecting S1 nerve roots. Using less local anesthetic may reduce this risk and improve diagnostic accuracy for lower back pain.
Area of Science:
- Pain Management
- Radiology
- Anatomy
Background:
- Sacroiliac (SI) joint dysfunction is a frequent cause of lower back pain.
- Diagnosing SI joint pain is challenging, with SI joint injections serving as a gold standard for diagnosis and therapy.
- A known complication of SI joint injection is temporary leg numbness and weakness.
Purpose of the Study:
- To evaluate SI joint anatomy and contrast flow during injections.
- To understand how local anesthetics may impact nerve roots, leading to temporary leg symptoms.
- To correlate imaging findings with potential neurological complications.
Main Methods:
- Retrospective case series design at an academic medical center.
- Review of patients undergoing SI joint injection with 3D cone beam CT (CBCT) fluoroscopy.
- Analysis of CBCT images to assess contrast spread within the SI joint and surrounding structures.
Main Results:
- 27 patients (mean age 56) were analyzed.
- 14.8% of patients showed contrast spread into the S1 posterior neuroforamen.
- 85.2% of patients had contrast confined to the SI joint.
Conclusions:
- Lower concentrations and volumes of local anesthetic may reduce the risk of S1 nerve root and epidural blocks.
- Consideration of S1 nerve pathology is important for accurate diagnosis of SI joint pain.
- Optimizing SI joint injection techniques can enhance diagnostic specificity and minimize complications.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Spinal Nerves: Plexus II
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Spinal Nerves: Anatomy
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Spinal Nerves: Plexus I
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...

