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Cell-free DNA analysis for recurrent respiratory papillomatosis: A case report
Satoshi Yamada1, Kotaro Kano1, Ryuji Ishikawa1,2
1Department of Otolaryngology/Head and Neck Surgery Hamamatsu University School of Medicine Hamamatsu Japan.
Clinical Case Reports
|August 8, 2024
Abstract:
A 35-year-old male presented with recurrent respiratory papillomatosis. Human papillomavirus type 11 was detected from all sites of tumor tissue DNA by PCR. The pre-surgery cell-free DNA (cfDNA) viral load (3.33 × 103 copies/ng DNA) fell below the post-surgical detection limits on achieving remission, suggesting cfDNA's potential as a biomarker.
