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Related Experiment Video

Updated: Jun 17, 2025

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity

Published on: January 6, 2015

Increased lung field permeability in young patients.

Ayaka Tanaka¹, Masamitsu Hamakawa¹, Tadashi Ishida¹

¹Department of Respiratory Medicine Ohara Healthcare Foundation, Kurashiki Central Hospital Okayama Japan.

Clinical Case Reports

|August 8, 2024

Summary

Pediatric lung hyperlucency on chest X-rays requires reviewing past childhood infections and prior imaging. This helps differentiate congenital from acquired causes, aiding in Swyer-James Syndrome (SJS) diagnosis.

Keywords:

SPECT/CT Swyer–James syndrome Swyer–James–MacLeod syndrome acquired chest X‐ray lung hyperlucency

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Area of Science:

Pediatric Radiology
Pulmonology

Background:

Lung hyperlucency on chest radiography in young patients can indicate various underlying conditions.
Differentiating congenital from acquired causes is crucial for accurate diagnosis and management.

Observation:

A key diagnostic clue for Swyer-James Syndrome (SJS) is unilateral lung hyperlucency on chest X-ray.
The presence of prior childhood infections is a significant factor in the clinical history.

Findings:

Reviewing previous chest radiographs is essential to assess the chronicity and nature of the lung abnormality.
Correlating radiographic findings with clinical history aids in distinguishing SJS from other causes of hyperlucency.

Implications:

Early and accurate diagnosis of SJS is vital for appropriate patient care and prognosis.
This diagnostic approach can prevent misdiagnosis and guide further investigations or treatments.