Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Enzymes02:34

Enzymes

81.2K
Inside living organisms, enzymes act as catalysts for many biochemical reactions involved in cellular metabolism. The role of enzymes is to reduce the activation energies of biochemical reactions by forming complexes with its substrates. The lowering of activation energies favor an increase in the rates of biochemical reactions.
Enzyme deficiencies can often translate into life-threatening diseases. For example, a genetic abnormality resulting in the deficiency of the enzyme G6PD...
81.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single-Molecule DNA Tweezers Enable Programmable Control of Enzyme Activity via Arbitrary Molecular Cues.

Angewandte Chemie (International ed. in English)·2025
Same author

33 Unresolved Questions in Nanoscience and Nanotechnology.

ACS nano·2025
Same author

Discovery of Surface-Engineered Nanoparticles That Boost Enzyme Activity via High-Throughput Screening and Machine Learning.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Voices in <i>Molecular Pharmaceutics</i>: Meet Dr. Sasha Ebrahimi, Manipulator of Molecules and Designer of Drug Delivery Systems to Enhance the Effectiveness of Therapeutics.

Molecular pharmaceutics·2025
Same author

Label-Free Quantification of DNA Loading on Centrifugation-Resistant Spherical Nucleic Acids.

Analytical chemistry·2025
Same author

Stereochemistry of Phosphorothioate Linkages Impacts the Structure and Binding Affinity of Aptamers and DNAzymes.

Molecular pharmaceutics·2025
Same journal

Reaction Optimization for Enzymatic Deconstruction of Industrially Relevant Nylon Composites.

Chembiochem : a European journal of chemical biology·2026
Same journal

Deploying Artificial Metalloenzymes in Complex Environments: Strategies and Applications.

Chembiochem : a European journal of chemical biology·2026
Same journal

Synthetic Ligands of Myeloid C-Type Lectin Receptors.

Chembiochem : a European journal of chemical biology·2026
Same journal

Vancomycin-Mediated Binding of DNA Origami Nanostructures to Gram-Positive and Gram-Negative Bacteria.

Chembiochem : a European journal of chemical biology·2026
Same journal

Mutasynthesis and Antibiotic Activity of Mupirocin Analogues.

Chembiochem : a European journal of chemical biology·2026
Same journal

Pressure-Dependent Aromatic Ring Flips Reveal Variable Transition-State Volume and Compressibility Among Structural Regions of BPTI.

Chembiochem : a European journal of chemical biology·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2025

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
10:50

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

16.3K

Modulating Enzyme Activity using Engineered Nanomaterials.

Atri Bhattacharya1, Subrata Pandit1, Seungheon Lee1

  • 1Department of Chemistry, The University of Texas at Austin, 105 E 24th St, Austin, TX, 78712, USA.

Chembiochem : a European Journal of Chemical Biology
|August 8, 2024
PubMed
Summary
This summary is machine-generated.

Nanomaterials modulate enzyme activity, offering new strategies for drug design and industrial applications. Immobilizing enzymes on nanomaterials enhances their performance and versatility.

Keywords:
ActivityEnzymesNanomaterialsNanoparticlesReversibility

More Related Videos

Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.6K
Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
11:16

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization

Published on: July 11, 2012

16.2K

Related Experiment Videos

Last Updated: Jun 17, 2025

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
10:50

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

16.3K
Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.6K
Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
11:16

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization

Published on: July 11, 2012

16.2K

Area of Science:

  • Biotechnology and Biochemistry
  • Materials Science

Background:

  • Enzymes are crucial in biotechnology; understanding their inhibition aids drug design.
  • Enzyme modulation, including inhibition and activity enhancement, is key for industrial processes.
  • Enzyme immobilization on nanomaterials is a rapidly developing area for tuning enzyme performance.

Purpose of the Study:

  • To highlight advancements in using nanomaterials for enzyme modulation.
  • To discuss the dual role of nanomaterials in inhibiting and enhancing enzyme activity.
  • To explore future prospects of nanomaterial-enzyme interactions in molecular systems and applications.

Main Methods:

  • Review of recent literature on nanomaterial-based enzyme immobilization.
  • Analysis of studies demonstrating nanomaterial effects on enzyme activity (inhibition and enhancement).
  • Exploration of the versatility of nanomaterials in enzyme modulation.

Main Results:

  • Nanomaterials can both inhibit and enhance enzyme activity.
  • Immobilization on nanomaterials offers a promising approach for tuning enzyme performance.
  • Nanomaterials demonstrate versatility in modulating biochemical pathways.

Conclusions:

  • Nanomaterial-based enzyme modulation presents significant opportunities for biotechnology.
  • Further research can lead to sophisticated molecular systems and novel downstream applications.
  • The dual role of nanomaterials in enzyme activity control is a key area for future development.