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ZEBRA study: The Z stitch Early Bed Rest Assessment study.

Adarsh Katamreddy¹, Ryle Przybylowicz¹, Jose Lozano Garcia¹

¹Division of Cardiology, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon.

Heart Rhythm O2

|August 9, 2024

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Early mobilization after Z-stitch venous access in electrophysiology procedures may improve patient satisfaction without compromising safety. The ZEBRA study assesses early ambulation benefits versus prolonged bed rest.

Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Patient Safety

Background:

Venous vascular access management is crucial for electrophysiology (EP) procedures.
The Z-stitch method offers effective venous hemostasis.
Prolonged bed rest post-procedure can negatively impact patient satisfaction.

Purpose of the Study:

To evaluate if early mobilization after Z-stitch placement enhances patient satisfaction.
To assess the safety of early mobilization compared to standard prolonged bed rest.
To quantify patient satisfaction metrics and safety parameters in EP procedures.

Main Methods:

Prospective, multicenter, randomized clinical trial of approximately 200 patients.
Random assignment to 1-hour or 4-hour bed rest post-Z-stitch.

Keywords:

Electrophysiology procedures Postprocedure management Randomized clinical trial Venous vascular hemostasis Z stitch

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Assessment of patient satisfaction via survey and monitoring of safety endpoints like hematomas and bleeding.

Main Results:

Anticipated higher patient satisfaction scores with early mobilization.
Close monitoring of hematomas, pain medication use, and healthcare costs.
Evaluation of 30-day patient outcomes, including ambulation time and groin complication-related visits.

Conclusions:

The ZEBRA study addresses a gap in post-EP procedure care knowledge.
Findings could influence future guidelines for venous vascular access management.
Early mobilization may improve patient experience and outcomes in EP procedures.