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Related Concept Videos

Regional Terms01:12

Regional Terms

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Regional terms describe anatomy by dividing the body parts into different regions that contain structures involved in contributing similar functions. Using these terms helps increase the accurate description and identification of the particular region of interest or region affected by the disease.
Primarily, the human body has two major regions, the axial and appendicular regions. The axial region comprises regions from the head to the abdomen and makes up the central body axis. In contrast,...
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Physiological Barriers01:25

Physiological Barriers

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Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
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Drug Distribution: Tissue Binding01:21

Drug Distribution: Tissue Binding

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Upon entering the systemic circulation, drugs can distribute into the interstitial and intracellular fluid of various tissue cells. This distribution is facilitated by the binding of drugs to different cellular components within tissues, which may lead to drug accumulation in specific areas. Drugs bound to tissue components serve as reservoirs that release free drugs back into the system, prolonging the drug's overall action. However, this accumulation can also result in local toxicity.
For...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
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The Blood-brain Barrier00:49

The Blood-brain Barrier

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Related Experiment Video

Updated: Jun 17, 2025

A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain
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A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain

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Boundarics in Biomedicine.

Quansheng Du1, Juan Li2, Fang Yang2

  • 1National Natural Science Foundation of China, Beijing 100085, China.

Research (Washington, D.C.)
|August 12, 2024
PubMed
Summary

Boundaries in Biomedicine is a new interdisciplinary field studying life

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Area of Science:

  • Interdisciplinary research at the intersection of bioscience, medicine, chemistry, materials science, and information science.

Background:

  • Understanding life's origins, organism-environment interactions, and disease mechanisms requires studying biological boundaries.
  • Boundaries in Biomedicine addresses key scientific questions in the formation, identification, and evolution of these boundaries.

Purpose of the Study:

  • To define Boundaries in Biomedicine, including its scope, methods, challenges, and future directions.
  • To highlight the significance of this field for fundamental biological understanding and medical applications.

Main Methods:

  • Investigating biological boundaries at three key levels: organism-environment, internal organismal, and disease-related.
  • Integrating knowledge and techniques from diverse scientific disciplines.

Main Results:

  • Established a definition and framework for the interdisciplinary field of Boundaries in Biomedicine.
  • Outlined the critical role of biological boundaries in life processes and disease.

Conclusions:

  • Research in Boundaries in Biomedicine is crucial for understanding life's origins and disease mechanisms.
  • This field offers novel approaches for disease diagnosis, prevention, drug development, and prognosis assessment.