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Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

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Updated: May 12, 2026

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
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Acute Bacterial Prostatitis Caused by Staphylococcus saprophyticus: A Case Report.

Christopher T Gabbert1, Fariha Bhuiyan1, Intekhab Askari Syed2,3

  • 1Medical School, Sentara Halifax Regional Hospital Clinical Site, Edward Via College of Osteopathic Medicine, Blacksburg, USA.

Cureus
|August 12, 2024
PubMed
Summary
This summary is machine-generated.

A rare case of acute bacterial prostatitis caused by Staphylococcus saprophyticus in a 46-year-old male resolved with antibiotic treatment. This highlights the need to consider unique bacterial causes and predisposing factors for effective prostatitis management.

Keywords:
acute bacterial prostatitislower urinary tract symptomsmale urologystaphylococcus saprophyticusurinary track infection

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Area of Science:

  • Urology
  • Infectious Diseases
  • Microbiology

Background:

  • Acute bacterial prostatitis presents with abrupt lower urinary tract symptoms, necessitating prompt treatment to avoid complications.
  • Common causative agents include Escherichia coli and Enterobacteriae species, but rarer pathogens require consideration.

Observation:

  • A 46-year-old male with no prior prostate issues presented with fever, chills, diarrhea, and resolved urinary symptoms.
  • Clinical workup revealed elevated prostate-specific antigen and a positive urinary culture for Staphylococcus saprophyticus.

Findings:

  • The patient's symptoms and elevated prostate-specific antigen levels significantly improved after seven days of antibiotic therapy.
  • Complete resolution of symptoms and normalization of prostate-specific antigen were observed after a 28-day antibiotic course.

Implications:

  • This case underscores Staphylococcus saprophyticus as a potential, albeit uncommon, cause of acute bacterial prostatitis.
  • Identifying predisposing factors and optimizing treatment strategies for rare bacterial prostatitis cases are crucial for clinical practice and future research.