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Updated: Jul 9, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Peri-implant bone changes after using platelet-rich fibrin scaffold among Indians
Abhishek Balani1, Jaishree Tandon1, Vinay Kharsan1
1Department of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India.
Abstract:
Bone transplant with osteopromotive elements - such as herbal extracts - that promote the creation of new boneis of interest to dentists. Hence, we compared the bone loss around dental implants while placing platelet rich fibrin (PRF) scaffold alone and PRF scaffold with simvastatin (SIM) and PRF scaffold with Moringaoleifera (MO). There were thirty six patients total. A total of 36 implants, or twelve implants in all three categories, were the estimated sample size. Category 1: PRF scaffolds alone. Category 2: PRF scaffolds with SIM. Category 3: PRF scaffolds with MO. Alteration in the bones were measured with CBCT. It was observed that there was decreased loss of crestal bone in PRF+ SIM and PRF+MO as compared to PRF alone. The use of herbal osteopromotive agents like simvastitin and Moringaoleifera along with PRF scaffolds can be effective in reducing bone loss around dental implants.
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