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Hemodynamic stability with clonidine versus adrenaline in mandibular third molar surgeries
Jyoti Bhavani Penumarti1, Vinay Kharsan1, Abhishek Balani1
1Department of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.
Abstract:
This randomized clinical trial compares 2% lignocaine with clonidine versus 2% lignocaine with adrenaline for impacted mandibular third molar surgery. Hence, 70 patients aged 18-40 were randomly allocated to either group. We evaluated hemodynamic stability, onset and duration of anesthesia. Clonidine showed lower intraoperative and postoperative systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and mean arterial pressure (MAP). Though onset was slightly slower with clonidine, hemodynamic control was superior. Clonidine appears to be a safer alternative for patients requiring cardiovascular stability.
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