Related Experiment Video

Updated: Apr 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.4K

Intravascular Lithotripsy vs Atherectomy in the Treatment of Calcified Common Femoral Artery Disease

Muhammad Baig1,2, Michael Kwok3, Ammer Aldairi4

  • 1Division of Cardiology, Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island.

Journal of the Society for Cardiovascular Angiography & Interventions
|August 12, 2024
PubMed

Insights

Intravascular lithotripsy with drug-coated balloons (IVL-DCB) showed comparable midterm effectiveness to atherectomy with drug-coated balloons (Ath-DCB) for common femoral artery disease. Both treatments demonstrated high safety and efficacy in this patient cohort.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Endovascular Therapy

Background:

  • Common femoral artery (CFA) disease often presents with heavy calcification, leading to suboptimal outcomes with endovascular treatments compared to surgical options.
  • While intravascular lithotripsy (IVL) shows promise short-term, its midterm effectiveness for CFA disease remains under-investigated.
  • This study compares IVL-DCB to atherectomy-DCB (Ath-DCB) for treating calcified CFA disease.

Purpose of the Study:

  • To compare the midterm effectiveness of IVL-DCB versus Ath-DCB in patients with symptomatic CFA disease.
  • To evaluate clinically driven target lesion revascularization (CD-TLR) rates as the primary endpoint.
  • To assess the safety and efficacy of these endovascular approaches.

Main Methods:

  • A single-center retrospective cohort study included 68 patients with symptomatic CFA disease treated between January 2015 and March 2020.
  • Patients received either IVL-DCB or Ath-DCB.
  • The primary outcome was cumulative CD-TLR, defined as restenosis ≥50%, analyzed using Kaplan-Meier and log-rank tests over 18 months.

Main Results:

  • Technical success was 100% in both groups, with minimal procedural complications requiring stenting.
  • Mean age was 72 years, predominantly male (63.3%) and White (92%).
  • Eighteen-month freedom from CD-TLR was 91.2% for Ath-DCB versus 79.4% for IVL-DCB (Log-rank P = .167), indicating comparable outcomes.

Conclusions:

  • IVL-DCB demonstrated comparable safety and effectiveness to Ath-DCB for treating calcified CFA disease over an 18-month follow-up period.
  • Both endovascular strategies appear to be viable options for managing complex CFA lesions.
  • Further prospective studies are warranted to confirm these midterm findings.
Abstract

Keywords:
Atherectomycommon femoral arteryintravascular lithotripsy

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.6K
Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

1.4K

Related Concept Videos

Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
592
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
589
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
454
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
293
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
466
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
867