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SCAI Guidelines for the Management of Patent Foramen Ovale

Clifford J Kavinsky1, Molly Szerlip2, Andrew M Goldsweig3

  • 1Rush University Medical Center, Chicago, Illinois.

Journal of the Society for Cardiovascular Angiography & Interventions
|August 12, 2024
PubMed

Insights

Patent foramen ovale (PFO) guidelines offer recommendations for patient selection for PFO closure to prevent stroke and other conditions. These guidelines address various clinical scenarios and identify future research needs.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Clinical Guidelines

Background:

  • Patent foramen ovale (PFO) is a common congenital heart structure in adults, usually benign.
  • PFO can lead to serious complications in specific circumstances.

Purpose of the Study:

  • To provide evidence-based guidelines for the management of Patent Foramen Ovale (PFO).
  • To support patients, clinicians, and stakeholders in PFO management decisions.

Main Methods:

  • A multidisciplinary panel convened by the Society for Cardiovascular Angiography and Interventions (SCAI) developed the guidelines.
  • The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used, including systematic reviews and evidence synthesis.
  • Recommendations were formulated based on evidence and contextual factors.

Main Results:

  • Thirteen recommendations were established to address five distinct clinical scenarios involving PFO.
  • Key recommendations focus on patient selection for PFO closure to prevent stroke.

Conclusions:

  • The guidelines address PFO closure for stroke prevention, including in populations not typically studied in randomized trials.
  • The role of PFO closure in preventing migraines and decompression illness is also considered.
  • Future research priorities for advancing PFO management have been identified.
Abstract

Keywords:
TBD

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