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Updated: Jun 17, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2,4-Quinolinedione alkaloids: occurrence and biological activities
Shahriar Khadem1, Robin J Marles2
1Safe Environments Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Canada.
None:
Natural products are an important source of chemical scaffolds that have diverse biological activities. They can be used directly or as starting templates for the development of innovative pharmaceutical agents. Among natural products, quinoline alkaloids are one of the most extensively studied groups. 2,4-Quinolinedione (2,4-QD) alkaloids, which are found in a variety of natural sources, possess valuable biological properties. This review examines the natural occurrence and bioactivities of 2,4-QD alkaloids, which have not been studied in as much depth in previous research.
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