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Updated: Jun 17, 2025

Automated Sholl Analysis of Digitized Neuronal Morphology at Multiple Scales
Published on: November 14, 2010
DNeuroMAT: A Deep-Learning-Based Neuron Morphology Analysis Toolbox
Min Liu1,2, Zhuangdian Lin3,4, Weixun Chen3,4
1College of Electrical and Information Engineering, Hunan University, Hunan, China. liu_min@hnu.edu.cn.
None:
Digital reconstruction of neuronal structures from 3D neuron microscopy images is critical for the quantitative investigation of brain circuits and functions. Currently, neuron reconstructions are mainly obtained by manual or semiautomatic methods. However, these ways are labor-intensive, especially when handling the huge volume of whole brain microscopy imaging data. Here, we present a deep-learning-based neuron morphology analysis toolbox (DNeuroMAT) for automated analysis of neuron microscopy images, which consists of three modules: neuron segmentation, neuron reconstruction, and neuron critical points detection.

