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Recent insights into the impacts of COVID-19 on pediatric asthma

Carolina da Silva Alves1,2, Raquel Baptista Pestana1, Mário Morais-Almeida1

  • 1Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal.

Expert Review of Clinical Immunology
|August 13, 2024
PubMed

Insights

COVID-19 generally does not worsen pediatric asthma, but uncontrolled asthma increases severe COVID-19 risk. Maintaining asthma control and vaccination are crucial for children with asthma during the pandemic.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Asthma Research

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, prompted extensive research into its effects on various health conditions, including pediatric asthma.
  • Understanding the interplay between SARS-CoV-2 infection and asthma in children is critical for effective management and public health strategies.

Purpose of the Study:

  • To review and synthesize current research on the impact of COVID-19 on pediatric asthma.
  • To explore clinical outcomes, immune responses, treatment modifications, and the role of vaccination in children with asthma during the pandemic.

Main Methods:

  • A narrative review of studies published from January 2020 to November 2023.
  • Data were collected from major scientific databases including PubMed, Embase, and preprint servers (BioRxiv/MedRxiv).

Main Results:

  • Asthma in children was not typically associated with an increased risk of severe COVID-19.
  • Uncontrolled asthma emerged as a significant risk factor for severe COVID-19 outcomes in pediatric populations.
  • Telemedicine demonstrated effectiveness in managing pediatric asthma during the pandemic.
  • Evidence suggests a potential protective effect of allergic asthma against severe COVID-19.

Conclusions:

  • Maintaining optimal asthma control is paramount for children during the COVID-19 pandemic.
  • COVID-19 vaccination is recommended for all children, including those with asthma.
  • Continued research is needed to clarify the complex interactions between SARS-CoV-2 and pediatric asthma.
Abstract

Keywords:
COVID-19SARS-CoV-2atopicpediatric asthmatreatmentvaccination

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