Hepatocellular carcinoma metastasis presenting as a pedunculated bladder mass
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Updated: Jun 17, 2025
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
Sarah Lorger1, George McClintock1, Geoffrey Watson2
1Urology Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Abstract:
Extrahepatic metastasis of hepatocellular carcinoma (HCC) is a sign of advanced disease with poor prognosis. Haematogenous metastasis to the urinary bladder is extremely rare. We describe a case of a 66-year-old male with advanced HCC that developed HCC metastasis to the bladder. There have only been six case reports previously documenting this. Uniquely this is the first case to develop metastatic disease to the bladder after receiving both locoregional and systemic therapy.
