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Updated: Jun 17, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Blood pressure variability as a risk factor of recurrent paroxysmal atrial fibrillation after catheter ablation

Minoru Yambe1, Yuki Kurose1, Kaoru Hasegawa1

  • 1Tohoku Medical and Pharmaceutical University Sendai Japan.

Journal of Arrhythmia
|August 14, 2024
PubMed

Insights

High blood pressure variability, measured by variability independent of the mean (VIM) of systolic blood pressure, is a significant risk factor for atrial fibrillation (AF) recurrence after catheter ablation (CA). This finding aids in predicting AF recurrence post-procedure.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Electrophysiology

Background:

  • Blood pressure variability (BPV) independently predicts cardiovascular events like stroke and heart failure.
  • Visit-to-visit BPV is increasingly recognized as a critical clinical parameter.
  • Catheter ablation (CA) is a common treatment for paroxysmal atrial fibrillation (PAF).

Purpose of the Study:

  • To evaluate visit-to-visit blood pressure variability using variability independent of the mean (VIM) in patients post-CA for PAF.
  • To examine the relationship between BPV and the recurrence of atrial fibrillation (AF) after CA.

Main Methods:

  • Analysis of 237 consecutive patients who underwent CA for PAF.
  • Measurement of systolic blood pressure variability independent of the mean (VIM SBP) during outpatient follow-up.
  • Utilized Cox proportional hazards models to assess risk factors for AF recurrence.

Main Results:

  • Patients experiencing AF recurrence had significantly higher VIM SBP compared to those without recurrence.
  • VIM SBP was a significant independent risk factor for AF recurrence post-CA (Hazard Ratio = 4.839).
  • Dihydropyridine calcium channel blockers were associated with a lower risk of AF recurrence.

Conclusions:

  • Elevated blood pressure variability, specifically VIM SBP, is a potential risk factor for AF recurrence following CA.
  • BPV assessment may improve risk stratification for patients undergoing CA for PAF.
  • Antihypertensive medication choice, such as dihydropyridine calcium channel blockers, may influence AF recurrence risk.
Abstract

Keywords:
antihypertensive drugsatrial fibrillationblood pressurecatheter ablationrecurrence

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