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Association between monosodium glutamate consumption with changes in gut microbiota and related metabolic dysbiosis-A

Hossein Ahangari1,2, Behnam Bahramian2, Arezou Khezerlou2

  • 1Student Research Committee Tabriz University of Medical Sciences Tabriz Iran.

Food Science & Nutrition
|August 14, 2024
PubMed

Insights

This systematic review examines how monosodium glutamate (MSG) affects the human gut microbiome, liver, and kidneys. It highlights the need for more research on MSG

Area of Science:

  • Gastroenterology and Hepatology
  • Microbiome Research
  • Toxicology

Background:

  • Monosodium glutamate (MSG) is a widely used food additive.
  • Existing research lacks a comprehensive analysis of MSG's impact on the human gut microbiome.
  • Understanding MSG's effects on gut flora is crucial for human health.

Purpose of the Study:

  • To systematically review the effects of MSG on the human gut microbiome.
  • To investigate the impact of MSG on liver and kidney function.
  • To identify potential links between MSG consumption and overall health.

Main Methods:

  • A systematic literature search was conducted across major scientific databases (PubMed, Scopus, Web of Science, ScienceDirect).
  • Specific search strategies and keywords were employed to identify relevant studies.
  • 14 eligible studies were selected for inclusion in the systematic review.

Main Results:

  • The review synthesizes findings from 14 studies on MSG's effects.
  • Identified impacts of MSG on gut microbiota composition and function.
  • Preliminary data suggests potential alterations in liver and kidney parameters due to MSG.

Conclusions:

  • This study provides a novel perspective on MSG's influence on gut flora.
  • Highlights a potential association between MSG intake and human health outcomes.
  • Emphasizes the need for further comprehensive research in this area.
Keywords:
dysbiosisfood additivegut microbiotamonosodium glutamate

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