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Blood Pressure Time in Target Range and its Impact on Clinical Outcomes
Astefanos Al-Dalakta1, Chadi Tabaja1, Issam Motairek1
1Department of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Achieving higher blood pressure (BP) time in target range significantly reduces cardiovascular risks, including heart failure and stroke. This metric offers valuable insights for hypertension management and patient outcomes.
Area of Science:
- Cardiology
- Hypertension Management
- Preventive Medicine
Background:
- Blood pressure (BP) management is crucial for cardiovascular health.
- Traditional BP metrics may not fully capture long-term cardiovascular risk.
- The concept of time in therapeutic range is gaining traction in managing chronic conditions.
Purpose of the Study:
- To review the concept of time in target range for blood pressure (BP) management.
- To explore methods for calculating BP time in target range.
- To assess its implications for patient outcomes and clinical care.
Main Methods:
- Analysis of recent post-hoc studies from clinical trials.
- Review of observational studies on BP management.
- Exploration of BP time in target range calculation and its correlation with outcomes.
Main Results:
- Higher BP time in target range is linked to reduced risks of major adverse cardiovascular events (MACE), including heart failure, stroke, myocardial infarction, and all-cause mortality.
- Increased time in target range also lowers the risk of atrial fibrillation and dementia.
- BP time in target range is a novel metric providing valuable insights into BP control and clinical outcomes.
Conclusions:
- BP time in target range is a significant predictor of cardiovascular outcomes across diverse patient populations.
- Further prospective trials and real-world studies are needed to fully establish its clinical application.
- Integrating continuous BP monitoring via wearable devices could enhance the utility of this metric in hypertension management.
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