Related Experiment Video
Updated: Jun 17, 2025

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Anesthesia considerations for pediatric metabolic and bariatric surgery
Katherine Manupipatpong1, Colton D Wayne2, Joseph D Tobias1
1Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, and The Ohio State University, College of Medicine, Columbus, USA.
Insights
Childhood obesity is a growing global concern, increasing surgical risks for children and adolescents. Anesthetic strategies must address obesity-related complications for safer metabolic and bariatric surgery.
Area of Science:
- Pediatric Anesthesiology
- Bariatric Surgery
- Obesity Medicine
Background:
- Childhood obesity presents a significant global health challenge with long-term morbidity and mortality.
- Obesity complicates various organ systems, leading to increased perioperative risks.
- Current treatments include lifestyle changes, medications, and increasingly, metabolic and bariatric surgery for adolescents.
Purpose of the Study:
- To outline key anesthetic considerations for pediatric and adolescent patients undergoing metabolic and bariatric surgery.
- To highlight the importance of preoperative optimization and management of comorbidities.
- To discuss specific anesthetic techniques and postoperative care strategies.
Main Methods:
- Comprehensive preoperative evaluation of comorbidities (hypertension, OSA, asthma, glycemic control).
- Consideration of antiobesity medications' effects on pharmacokinetics and hemodynamics.
- Application of advanced airway management, targeted ventilation, and opioid-sparing analgesia.
- Implementation of enhanced recovery after surgery (ERAS) protocols.
Main Results:
- Anesthetic management requires careful attention to airway, ventilation, and pharmacologic adjustments.
- Preoperative optimization and management of comorbidities are crucial for mitigating risks.
- ERAS protocols show promise in reducing complications and length of stay.
Conclusions:
- Metabolic and bariatric surgery is a viable option for adolescents with severe obesity.
- Tailored anesthetic and surgical care is essential for improving outcomes in this population.
- Multidisciplinary approaches enhance patient safety and recovery.
Abstract:
Childhood obesity is a rapidly growing global health issue, linked to significant lifelong morbidity and mortality. Its impact on various organ systems increases perioperative complications. Obesity treatment in children and adolescents involves lifestyle, dietary, and behavioral modifications, as well as pharmacologic interventions that targets hormonal, metabolic, and neurochemical abnormalities. Metabolic and bariatric surgery, proven safe and effective for adults with severe obesity (class 2 or higher), is now being recommended for adolescents. Key anesthetic considerations for these surgeries include preoperative optimization, advanced airway management, targeted ventilation strategies, and opioid-sparing analgesic regimens. Comprehensive presurgical evaluations must address co-morbid conditions such as hypertension, obstructive sleep apnea, asthma, and impaired glycemic control. Preoperative management should also consider the effects of antiobesity medications on gastric emptying and hemodynamic stability. Ventilation strategies should prevent atelectasis while avoiding barotrauma, and drug dosages must be adjusted for altered pharmacokinetics due to increased adipose tissue. Employing enhanced recovery after surgery protocols may reduce perioperative complications, shorten postsurgical stays, and improve outcomes.
Related Concept Videos
Parenteral Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Inhalational Anesthetics: Overview
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Stages of General Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia

